Inter-individual variability in equine antibody responses to African snake venoms follows heavy-tailed distributions with implications for antivenom production

Posted by
  Inter-individual variability in equine antibody responses to African snake venoms follows heavy-tailed distributions with implications for antivenom production Abstract Variability in the antibody response of horses used for snake antivenom manufacture is well recognized, yet its statistical structure and implications for industrial productivity remain poorly characterized. In this study, we quantified antivenom antibody titers by ELISA in a cohort of 14 horses immunized with venoms from the clinically most important snakes in sub-Saharan Africa. To integrate antibody levels with plasma availability, we calculated the Cumulative Plasma Productivity (CPP) by converting individual plasma volumes into titer-corrected equivalents and sequentially pooling these volumes according to their corrected contribution. Distributional analysis revealed right-skewed, heavy-tailed patterns better approximated by a log-normal model than by a strict Pareto (power-law) form, with approximately 20–3...

Mygalomorph spiders from Peru (Araneae, Pycnothelidae, Rhytidicolidae): description of two new species and first Peruvian record of the family Rhytidicolidae

Posted by

 


Mygalomorph spiders from Peru (Araneae, Pycnothelidae, Rhytidicolidae): description of two new species and first Peruvian record of the family Rhytidicolidae

Abstract

Two previously unknown mygalomorph spider species belonging to two families are described from the south-central Andean region of Peru. Within the family Pycnothelidae, Acanthogonatus goloboffi sp. n. is described, diagnosed and illustrated based on a female from Ccochirhuay, Cusco. The female of this species differs from most known Acanthogonatus by the shape of the spermathecae, which possess two single receptacles lacking additional projections or chambers. It further differs from congeners sharing a single receptacle by having non-spiraled ducts with a well-defined constriction and outwardly directed spherical receptacles. This represents the second record of the genus Acanthogonatus in Peru. Within the family Rhytidicolidae, Fufius agualaniensis sp. n. is described, diagnosed and illustrated based on a female from Agualani, Puno. The female of this species is distinguished from congeners by the following combination of characters: a straight fovea; a sternum as wide as long; a labiosternal junction with a well-developed septum; a preening comb on metatarsus IV consisting of seven large spines in a single row; and spermathecae with a wide, inwardly curved stalk giving rise to three sinuous branches ending in digitiform or domed structures. This constitutes the first formal record of the family Rhytidicolidae from Peru.

Beratz, M. J., Ferretti, N. E., Chaparro, J. C., & West, R. C. (2026). Mygalomorph spiders from Peru (Araneae, Pycnothelidae, Rhytidicolidae): description of two new species and first Peruvian record of the family Rhytidicolidae. Zoodiversity, 60(2). https://doi.org/10.15407/zoo2026.02.109