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Bioactive treasures in scorpion exuviae: anticancer insights from Hottentotta saulcyi extract fractions

  Bioactive treasures in scorpion exuviae: anticancer insights from Hottentotta saulcyi extract fractions Abstract Despite significant improvements in cancer treatment, the development of therapeutic resistance remains a major cause of treatment failure. Therefore, the discovery of new anticancer agents is still necessary. Scorpions have a long history of use in traditional and specialized medicines, including anticancer applications, and have shown promise in modulating biological processes. They are of medical importance both globally and in the Kurdistan Region. However, there is still limited scientific evidence regarding their potential in cancer therapy. This study evaluated the natural organic compounds of whole-body scorpion extracts using GC–MS analysis and determined the in vitro cytotoxic effects of n-hexane (HO-Hex) and methanol (HO-Me) extracts against SW480, Calu-6, PC-3, HT29, AGS, and LNCaP cancer cell lines. The MTT assay was used to determine the effects of the ex...

Bioactive treasures in scorpion exuviae: anticancer insights from Hottentotta saulcyi extract fractions

Bioactivity profiling of linear venom peptides from Italian small wood-scorpion (Euscorpius italicus)

DNA Barcoding Supports Species Delimitation in 11 Scorpion (Arachnida: Scorpiones) from Khuzestan Province, Southwestern Iran

A further new species for the genus Ananteris Thorell, 1891 (Scorpiones: Ananteridae) from a poorly prospected region of Brazilian Amazonia

Variability of sodium channel toxins in Mesobuthus thersites Advised toolkit for comprehensive venomics

One more new species of Chaerilobuthus Lourenço & beigel, 2011 (Scorpiones: Chaerilobuthidae) from Early Cretaceous Burmite

Cicileus derradji sp. nov., a New Species from Southern Algeria (Scorpiones: Buthidae)

Identification and expression analysis of antibacterial peptides from venom of the scorpion Mesobuthus martensii

Compsobuthus lakkiansis sp. nov. (Scorpiones: Buthidae), New Species from Pakistan

Two new arthropod toxins purified from the venom of the Mexican scorpion Centruroides nigrescens

Venom composition of the scorpion Chactas exsul (Scorpiones: Chactidae) from the Premontane tropical rainforest of Costa Rica

Climatic and density-dependent drivers of population dynamics in a hazardous urban scorpion species over seven years

Catalogue of the scorpions of Paraguay, with an illustrated key and biogeographical assessment (Arachnida: Scorpiones: Ananteridae, Bothriuridae, Buthidae)

Distribution of scorpions (arachnida: scorpiones) according to inaturalist observations in Panama

Scorpio basraensis sp. n. from southern Iraq (Scorpiones: Scorpionidae)

Venom Mass Fingerprints for Species Delimitation, Reloaded: A Test Case with Italian Scorpions (Euscorpius)

Morphometrical Variation in Buthus tunetanus (Scorpiones: Buthidae) from Tunisia

Ancient Divergence, Recent Island: Microplate Fragmentation and Dispersal Explain Disjunct Distributions of Western Mediterranean Scorpions

Computational engineering of the scorpion venom peptide Ttap3 enhances membrane selectivity and antimicrobial potential