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Antivenom Therapy for Medically Important Spiders in the United States

  Image Credit: Wikipedia Antivenom Therapy for Medically Important Spiders in the United States Luis A. Roque Arácnido Taxonomy Black widow envenomation caused by Latrodectus spp. can be managed with targeted antivenom therapy, whereas no equivalent approved therapy exists for brown recluse envenomation caused by Loxosceles spp. This contrast reflects the uneven development of spider-venom therapeutics in the United States. Introductory summary. In the United States, severe black widow envenomation can be treated with a targeted antivenom, whereas no comparable approved therapy exists for brown recluse envenomation (Clark et al., 1992; Swanson and Vetter, 2005). This disparity reflects differences in venom biology, therapeutic development, and the quality of available clinical evidence. Clinical Context Spiders occupy an important place in natural ecosystems, and only a small number are associated with medically significant bites in the United States. Most suspected spider bite...

Venom gland transcriptomics and bioactivity profiling suggest bifunctional hyaluronidase activity in the venom of Mesobuthus crucittii (Scorpiones: Buthidae)

Ontogenetic and geographic venom variation in the Great Basin Rattlesnake, Crotalus oreganus lutosus

Urban Spider Assemblages in a Neotropical City: Diversity, Functional Composition, and Introduced Species in Public Parks of Chetumal, Mexico

A new species of Strotarchus Simon, 1888 from Mexico and description of the male of the type species S. nebulosus Simon, 1888 (Araneae: Cheiracanthiidae)

A review of Idiommata Ausserer, 1871 (Mygalomorphae: Barychelidae), with the description of a related new genus and new species of giant Australian brush-footed spiders

Compsobuthus hadeki sp. n. from Iraq (Scorpiones: Buthidae)

Egg-Carrying and Cheliceral Comb in Ibaloniinae Harvestmen From the Solomon Islands (Opiliones: Podoctidae)

Huntsman spiders of the genus Sinopoda (Araneae, Sparassidae, Heteropodinae) from the Honghe Hani and Yi Autonomous Prefecture, southwestern China, with descriptions of two new species

Multidimensional toxicity of snake venom causes multi-organ damage and treatment challenges: a narrative review

A new Nemesia species from Spanish Catalonia (Araneae, Mygalomorphae, Nemesiidae, Haplonemesia)

Mechanism of Anticoagulation, Inhibition of In Vivo Thrombus Formation, and Assessment of Preclinical Safety of a Snake Venom Phospholipase A2 Enzyme-inspired New Antithrombotic Custom Peptide

First fossil of the pseudoscorpion family Chernetidae Menge, 1855 (Arachnida, Pseudoscorpiones) from mid-Cretaceous Burmese amber

Beyond morphology alone: species delimitation, hemispermatophore comparisons and comments on the systematic status of Scorpiops Peters, 1861 (Scorpiones: Scorpiopidae) with a description of three new species from peninsular India

Venom Variation as a Window into the Ecology and Evolution of Snakes

Passing of Petra Sierwald

ECOLOGICAL NICHE MODELS BY TITYUS SERRULATUS LUTZ & MELLO, 1922 AND TITYUS STIGMURUS (THORELL, 1876) (ARACHNIDA: SCORPIONES)