Scorpion Venom Peptides: From Structural Scaffolds to Therapeutic Applications—A Focus on Antioxidant Mechanisms and Translational Perspectives

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  Scorpion Venom Peptides: From Structural Scaffolds to Therapeutic Applications—A Focus on Antioxidant Mechanisms and Translational Perspectives Abstract Scorpion venom peptides, with their stable disulfide backbone, compact structural framework, and highly selective regulation of ion channels, have long been regarded as important molecular probes in neuropharmacology. However, recent studies have revealed their potential for regulating oxidative stress, inflammation, and neuroprotection, making them a new research frontier. In this article, we focus on scorpion venom peptides as drugs, constructing an integrated knowledge framework from structural classification to clinical translation. First, scorpion venom peptides are systematically classified based on cysteine arrangement patterns and three-dimensional folding topology, and their structure–activity relationships are summarized. Based on this, the molecular mechanisms by which scorpion venom peptides regulate ion channels are ...

Contributions to the knowledge of Mauritian araneofauna: new records (Araneae: Araneomorphae) and description of a remarkable new species of intertidal trapdoor spider (Araneae: Barychelidae)

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Contributions to the knowledge of Mauritian araneofauna: new records (Araneae: Araneomorphae) and description of a remarkable new species of intertidal trapdoor spider (Araneae: Barychelidae)

Abstract

We provide faunistic records of spiders from Mauritius, including 14 species new to the archipelago, representing a 27.45% increase in known spider diversity. We describe a new flagship endemic species of intertidal trapdoor spider: Idioctis marevallum sp. nov.; in addition, we provide observations and photographs of its burrow structure and general habitat.

Acknowledgment: I would like to extend my sincere thanks to Danni Sherwood for providing the complete manuscript.

Sherwood, Danniella. (2026). Contributions to the knowledge of Mauritian araneofauna: new records (Araneae: Araneomorphae) and description of a remarkable new species of intertidal trapdoor spider (Araneae: Barychelidae). Arachnology. 20. 608-622.