Distinct pathophysiological mechanisms of Heterometrus laoticus and Lychas mucronatus scorpion venoms on cardiovascular and renal functions

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  Distinct pathophysiological mechanisms of Heterometrus laoticus and Lychas mucronatus scorpion venoms on cardiovascular and renal functions Abstract Background:    Heterometrus laoticus and Lychas mucronatus are widely distributed in Southeast Asia, yet their pathophysiological effects of both venoms remain poorly characterized due to low human fatality rates. This study compared their venom compositions and acute cardiovascular and renal effects. Methods:   Anesthetized male New Zealand White rabbits were monitored for blood pressure (BP), heart rate (HR), and renal clearance following intravenous administration of crude venom (0.5 mg/kg). Venom components were identified via LC-MS/MS, and hematological/biochemical parameters were assessed. Results:    H. laoticus venom induced a rapid, transient hypotension ( p < 0.05), followed by a mild, prolonged hypotensive phase (up to 120 min). Conversely, L. mucronatus venom elicited a biphasic response: ...

A Case of Severe Envenoming by a Featherleg Baboon Spider in Côte d'Ivoire

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A Case of Severe Envenoming by a Featherleg Baboon Spider in Côte d'Ivoire

Case Report

We report a case of Stromatopelma calceatum envenoming with magnetic resonance imaging-confirmed venom-induced fasciitis in a French legionnaire deployed to Côte d’Ivoire. Outcome was favorable following symptomatic treatment.

Acknowledgment: I extend my sincere appreciation to Danni Sherwood for drawing my attention to this publication.

Julien Dezile, Christine Rollard, Vladimir Totolidis, Georges Pfister, Jonathan Treille, Scott A Weinstein, Olivier Aoun, A Case of Severe Envenoming by a Featherleg Baboon Spider in Côte d'Ivoire, Journal of Travel Medicine, 2025;, taaf082, https://doi.org/10.1093/jtm/taaf082