Distinct pathophysiological mechanisms of Heterometrus laoticus and Lychas mucronatus scorpion venoms on cardiovascular and renal functions

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  Distinct pathophysiological mechanisms of Heterometrus laoticus and Lychas mucronatus scorpion venoms on cardiovascular and renal functions Abstract Background:    Heterometrus laoticus and Lychas mucronatus are widely distributed in Southeast Asia, yet their pathophysiological effects of both venoms remain poorly characterized due to low human fatality rates. This study compared their venom compositions and acute cardiovascular and renal effects. Methods:   Anesthetized male New Zealand White rabbits were monitored for blood pressure (BP), heart rate (HR), and renal clearance following intravenous administration of crude venom (0.5 mg/kg). Venom components were identified via LC-MS/MS, and hematological/biochemical parameters were assessed. Results:    H. laoticus venom induced a rapid, transient hypotension ( p < 0.05), followed by a mild, prolonged hypotensive phase (up to 120 min). Conversely, L. mucronatus venom elicited a biphasic response: ...

Description of a new Eratigena Bolzern, Burckhardt & Hänggi, 2013 (Arachnida: Araneae: Agelenidae) from the Balkans based on an integrative approach

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Description of a new Eratigena Bolzern, Burckhardt & Hänggi, 2013 (Arachnida: Araneae: Agelenidae) from the Balkans based on an integrative approach

Abstract

New data on agelenid spiders of the Balkans are provided. A new species of the genus Eratigena Bolzern, Burckhardt & Hänggi, 2013, Eratigena mirusha sp. nov. (♂/♀) from the Koznik Mountain in Kosovo is described, based on molecular and morphological data. The males Eratigena mirusha sp. nov. are most similar to E. agrestis (Walckenaer) but possess differently shaped conductor and retrolateral tibial apophysis. Females of both species differ in the shape of the epigyne and the posterior sclerite and from the positions of the copulatory openings, and the epigynal pseudo teeth. The genetic divergence calculated based on the barcode region of the cytochrome c oxidase subunit I gene (COI) confirms the morphological distinctness and supports Eratigena mirusha sp. nov. as a sister species of E. agrestis.

Geci, D., Ibrahimi, H., Naumova, M., Bilalli, A., Kolbmüller, S., Musliu, M., Grapci-Kotori, L., Gashi, A., Schäffer, S. & Wagner, M. (2025b). Description of a new Eratigena Bolzern, Burckhardt & Hänggi, 2013 (Arachnida: Araneae: Agelenidae) from the Balkans based on an integrative approach. Zootaxa 5636(1): 144-162. doi:10.11646/zootaxa.5636.1.