First chance to see: New jumping-spider species from Batanta, Indonesia (Araneae, Salticidae, Euophryini)

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  First chance to see: New jumping-spider species from Batanta, Indonesia (Araneae, Salticidae, Euophryini) Abstract The first spider records of Batanta, Birie, and Arefi islands, Raja Ampat, Indonesia are presented in this study. Three new species in the genus Canama Simon, 1903, Canama horobi sp. nov . (male), Canama limagigi sp. nov . (male) and Canama wanita sp. nov . (female) are described. Two Indonesian salticids, originally placed in Bathippus Thorell, 1892 and known from their original descriptions only, Bathippus dentiferellus Strand, 1911 and Bathippus seltuttensis Strand, 1911, are redescribed and illustrated. Due to their morphological similarity to the type species, three new combinations have been proposed: Canama dentiferellus (Strand, 1911), comb. nov ., Canama seltuttensis (Strand, 1911), comb. nov . and Canama dilanians (Thorell, 1881), comb. nov . To confirm the phylogenetic placement of the new species, we carried out a small phylogenetic anal...

Lansbermin-I, a disintegrin from Porthidium lansbergii lansbergii venom as a potential anticancer prototype: In vitro and in silico effects on cervical cancer cells

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Lansbermin-I, a disintegrin from Porthidium lansbergii lansbergii venom as a potential anticancer prototype: In vitro and in silico effects on cervical cancer cells

Abstract

We report the cytotoxic effects of Lansbermin-I, a disintegrin from Porthidium lansbergii lansbergii venom, on HeLa cervical cancer cells but not on leukemic, non-tumorigenic peripheral blood mononuclear cells (PBMCs) or fibroblast lines. Lansbermin-I reduced HeLa cell viability in a concentration-dependent manner, impaired adhesion to fibronectin and collagen, and inhibited migration and clonogenicity. Docking analysis suggested interaction with the RGD domain of integrin α5β1. These results identify Lansbermin-I as a potential antitumor prototype against cervical cancer.
Osorno-Valencia, D., Montoya-Gómez, A., Sevilla-Sánchez, M. J., Burbano-Guerrero, N., Mosquera-Escudero, M., & Jiménez-Charris, E. (2026). Lansbermin-I, a disintegrin from Porthidium lansbergii lansbergii venom as a potential anticancer prototype: In vitro and in silico effects on cervical cancer cells. Toxicon, 109063. https://doi.org/10.1016/j.toxicon.2026.109063