Role of snake venom proteases and tissue factor in venom induced hemostatic disorders and local hemorrhage in mice

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  Role of snake venom proteases and tissue factor in venom induced hemostatic disorders and local hemorrhage in mice Abstract Bothrops jararaca venom (BjV) induces hemostatic and inflammatory manifestations. Tissue factor (TF) is essential for hemostasis, but aberrant TF expression can cause coagulopathy. We determined the effect of inhibition of BjV serine proteases and metalloproteinases, as well as host TF, on the systemic coagulopathy and local hemorrhage in envenomed mice. Venom serine proteases induced hypofibrinogenemia whereas venom metalloproteinases induced hemorrhage. TF did not contribute to venom-induced coagulopathy, but played a protective role in venom-induced bleeding in mice. Sachetto, A. T., Mackman, N., & Santoro, M. L. (2026). Role of snake venom proteases and tissue factor in venom induced hemostatic disorders and local hemorrhage in mice. Toxicon , 109299. https://doi.org/10.1016/j.toxicon.2026.109299

A new spider species of Scytodes Latreille, 1804 from Jiangxi Province, southern China (Araneae, Scytodidae)

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A new spider species of Scytodes Latreille, 1804 from Jiangxi Province, southern China (Araneae, Scytodidae)

Background

Despite the increasing discovery of new spider species in Jiangxi Province, most are entelegynes or mygalomorphs, with haplogyne spiders being seldom reported. However, during a decade-long survey of spiders in Jinggangshan National Nature Reserve, two species of Scytodes were identified, including one known species, S. liui Wang, 1994 and one new species.

New information

A new species, Scytodes tanjiashui Liu, sp. nov., is described from Jinggangshan National Nature Reserve, Jiangxi Province, China. Morphological illustrations, SEM pictures, ink drawing, DNA barcode, photos of live specimens and a distribution map are given. The total number of the known species of Scytodes from China is raised to 11.

Shi Y, Liu P, Yao Y, Liu K (2026) A new spider species of Scytodes Latreille, 1804 from Jiangxi Province, southern China (Araneae, Scytodidae). Biodiversity Data Journal 14: e181164. https://doi.org/10.3897/BDJ.14.e181164