Scorpion Venom Peptides: From Structural Scaffolds to Therapeutic Applications—A Focus on Antioxidant Mechanisms and Translational Perspectives

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  Scorpion Venom Peptides: From Structural Scaffolds to Therapeutic Applications—A Focus on Antioxidant Mechanisms and Translational Perspectives Abstract Scorpion venom peptides, with their stable disulfide backbone, compact structural framework, and highly selective regulation of ion channels, have long been regarded as important molecular probes in neuropharmacology. However, recent studies have revealed their potential for regulating oxidative stress, inflammation, and neuroprotection, making them a new research frontier. In this article, we focus on scorpion venom peptides as drugs, constructing an integrated knowledge framework from structural classification to clinical translation. First, scorpion venom peptides are systematically classified based on cysteine arrangement patterns and three-dimensional folding topology, and their structure–activity relationships are summarized. Based on this, the molecular mechanisms by which scorpion venom peptides regulate ion channels are ...

A new species of Trachelas L. Koch, 1872 in the bispinosus-group from Colombia (Araneae: Trachelidae)

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A new species of Trachelas L. Koch, 1872 in the bispinosus-group from Colombia (Araneae: Trachelidae)

Abstract
Trachelas amacayacu sp. nov. is described from Amacayacu National Park, Amazonas Department, Colombia based on a holotype female with distinct genital morphology. The type was deposited in the Manchester Museum (MMUE), Manchester, UK. Trachelas nigrifemur Mello-Leitão, 1941 from Cúcuta, Norte de Santander, Colombia is proposed as a nomen dubium.

Sherwood, Danniella & Buelvas, Diana. (2025). A new species of Trachelas L. Koch, 1872 in the bispinosus-group from Colombia (Araneae: Trachelidae). Revista Ibérica de Aracnología. 47. 87-89.