Advancements in Understanding Snake Venom: A Comprehensive Review of Biochemical Composition, Pharmacological Properties, and Therapeutic Applications

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Advancements in Understanding Snake Venom: A Comprehensive Review of Biochemical Composition, Pharmacological Properties, and Therapeutic Applications

Abstract

Snake venom, a complex mixture of bioactive molecules evolved for predation and defence, has captivated researchers for its diverse pharmacological properties and therapeutic potential. This review comprehensively examines the composition, mechanisms of action, clinical manifestations of envenomation, and therapeutic applications of snake venom components. We look into the complex interplay between venom toxins and their targets within the prey's body, elucidating the pathophysiological effects of envenomation on humans and animals. Antivenom therapy, the primary treatment modality for snakebite envenomation, is discussed in detail, highlighting challenges in accessibility, efficacy, and future directions for improvement. Furthermore, we explore the burgeoning field of venom-based drug discovery, showcasing innovative approaches to pain management, cancer therapy, and neurological disorders. With a focus on interdisciplinary collaboration, biotechnological innovation, and community engagement, we envision a future where snake venom research translates into impactful solutions for global health challenges. This review underscores the importance of understanding and harnessing the therapeutic potential of snake venom, paving the way for novel treatments and interventions that benefit human and animal well-being worldwide.

Anjan Kumar Chanda. 2025. “Advancements in Understanding Snake Venom: A Comprehensive Review of Biochemical Composition, Pharmacological Properties, and Therapeutic Applications”. Asian Journal of Research in Zoology 8 (4):81–102. https://doi.org/10.9734/ajriz/2025/v8i4222.