Ovophis tonkinensis envenoming presenting with severe isolated thrombocytopenia and local necrosis: A case report

  Image Credit: iNaturalist (c) randall_f –  some rights reserved (CC BY-NC) Ovophis tonkinensis envenoming presenting with severe isolated thrombocytopenia and local necrosis: A case report Abstract Pit viper envenoming commonly causes venom-induced consumption coagulopathy with hypofibrinogenaemia. However, isolated thrombocytopenia without fibrinogen depletion is less recognised and may alter transfusion strategy. We report a confirmed  Ovophis tonkinensis  bite from northern Vietnam presenting with severe isolated thrombocytopenia and local necrosis. The case highlights the importance of serial platelet monitoring, awareness of fibrinogen availability and appropriate timing of antivenom and platelet support in resource-limited tropical settings. Duc ND, Hong Anh LN, Hong Khanh LN, Bach ND. Ovophis tonkinensis envenoming presenting with severe isolated thrombocytopenia and local necrosis: A case report. Tropical Doctor . 2026;0(0). doi: 10.1177/00494755261435153

Omics Description (Metabolome and Microbiome) from Centuroides suffusus and Centuroides vittatus (Arachnida: Scorpiones)

 

By Drini (Pedro Sánchez) - Own work, CC BY 2.5, https://commons.wikimedia.org/w/index.php?curid=1912027

Omics Description (Metabolome and Microbiome) from Centuroides suffusus and Centuroides vittatus (Arachnida: Scorpiones)

Abstract

Scorpions are characterized by their venomous adaptations, including specialized stingers, and their ecological diversity. Some families, such as Buthidae, have medically significant species and their venoms possess a diverse array of chemicals. In Mexico, Centruroides suffusus and Centruroides vittatus coexist, with C. suffusus considered medically important due to its highly toxic venom. This study describes the metabolomic and microbiomic profiles of C. suffusus and C. vittatus. The metabolomic profiling (12 amino acids and 28 acylcarnitines) reveals significant differences between the two species, hinting at metabolic and ecological variations. Ornithine (ORN) and arginine (ARG) were the most abundant in C. vittatus, while tyrosine (TYR) was the most abundant amino acid molecule in C. suffusus. The microbiome analysis (by Next-Generation Sequencing of the 16S ribosomal gene) indicates similarities in gut bacteria composition between the two species (Phyla: Actinobacteria, Bacteroidetes, Cyanobacteria, Firmicutes, Proteobacteria and Tenericutes).

Lizbeth, M., Adrián, P., De Luna, M., Elia, L., Moises, C., L., M., E., A., & P., I. (2025). Omics Description (Metabolome and Microbiome) from Centuroides suffusus and Centuroides vittatus (Arachnida: Scorpiones). Arthropoda, 3(4), 14. https://doi.org/10.3390/arthropoda3040014