Spider bites, particularly from Loxosceles species, pose a public health concern in Mexico. A case of systemic loxoscelism in a 33-year-old woman who developed acute intravascular hemolysis is presented. The patient was successfully treated with blood transfusions and Reclusmyn, a Mexican antivenom. Her clinical and laboratory improvement supports the therapeutic value of antivenom in severe envenomation. This case highlights the importance of early suspicion, recognition, and targeted treatment to prevent complications and improve outcomes.
Guadarrama-Fernández C, Longino J A, Villalba-Ríos N, et al. (September 05, 2025) Successful Management of Intravascular Hemolysis Caused by Systemic Loxoscelism With Antivenom: A Case Report. Cureus 17(9): e91678. doi:10.7759/cureus.91678