Biofactories Applied to Future Antivenom Production

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  Image Credit: By Ssiltane - Own work, CC BY-SA 4.0, https://commons.wikimedia.org/w/index.php?curid=52242648 Biofactories Applied to Future Antivenom Production Abstract Background: Accidents caused by the  Loxosceles laeta  spider constitute a health problem in South America. Envenomation can lead to severe systemic manifestations, eventually compromising the patient’s life. Most regional health authorities consider antivenom administration the basis of effective treatment in the most serious cases. The availability of spider venom is the primary bottleneck for antivenom production. Herein, we present a novel biotechnological approach, based on the expression of recombinant versions of the most relevant toxin in loxoscelism, sphingomyelinase D (SphD), in insect larvae ( Spodoptera frugiperda ).  Methods: We produced two versions of SphD: one conserving its biological activities (wtSphD) and a second alternative that was designed to be genetically detoxified (dSphD...

A new Alpiscorpius from İstanbul Province of Turkey (Scorpiones: Euscorpiidae)

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A new Alpiscorpius from İstanbul Province of Turkey (Scorpiones: Euscorpiidae)

Abstract

A new scorpion species, Alpiscorpius istanbulensis sp. n., from Istanbul Province, Turkey, is described based on morphological and molecular evidence, raising to 19 the Euscorpiinae species, including 12 related to the genus Alpiscorpius or phylogenetically close at it.

Tropea, G., Yağmur, E. A., & Parmakelis, A. (2024). A new Alpiscorpius from İstanbul Province of Turkey (Scorpiones: Euscorpiidae). Biologia Serbica, 46. https://doi.org/10.5281/zenodo.13337532