Scorpion Venom Peptides: From Structural Scaffolds to Therapeutic Applications—A Focus on Antioxidant Mechanisms and Translational Perspectives

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  Scorpion Venom Peptides: From Structural Scaffolds to Therapeutic Applications—A Focus on Antioxidant Mechanisms and Translational Perspectives Abstract Scorpion venom peptides, with their stable disulfide backbone, compact structural framework, and highly selective regulation of ion channels, have long been regarded as important molecular probes in neuropharmacology. However, recent studies have revealed their potential for regulating oxidative stress, inflammation, and neuroprotection, making them a new research frontier. In this article, we focus on scorpion venom peptides as drugs, constructing an integrated knowledge framework from structural classification to clinical translation. First, scorpion venom peptides are systematically classified based on cysteine arrangement patterns and three-dimensional folding topology, and their structure–activity relationships are summarized. Based on this, the molecular mechanisms by which scorpion venom peptides regulate ion channels are ...

First record of Stenoterommata platensis (Araneae: Pycnothelidae) in Santiago del Estero, Argentina and niche modelling to unveil its distributional pattern

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Photo 332815205, (c) Rocío Esmeralda Pose, some rights reserved (CC BY), uploaded by Rocío Esmeralda Pose

First record of Stenoterommata platensis (Araneae: Pycnothelidae) in Santiago del Estero, Argentina and niche modelling to unveil its distributional pattern

ABSTRACT

Stenoterommata platensis is distributed in Argentina and Uruguay along the La Plata River basin, characterized by a predominantly humid climate and moist habitats. However, this contribution reports the presence of S. platensis outside its known distribution range, accompanied by an analysis of distribution models to assess the influence of bioclimatic variables on distribution patterns. This research confirms the current presence of S. platensis in the Santiago del Estero province, indicating a significant expansion of its geographic range and its ability to thrive in drier and high-temperature environments. Niche modeling under past conditions (~20000 years ago) indicated suitable areas for the establishing of this species in the Dry Chaco.

Nicoletta, Micaela & Ferretti, Nelson. (2024). First record of Stenoterommata platensis (Araneae: Pycnothelidae) in Santiago del Estero, Argentina and niche modelling to unveil its distributional pattern. 2023. 1-9. 10.54905/disssi.v24i74.e89s1606.