Venom composition of the Iberian adder (Vipera seoanei) from northern Portugal reveals limited sex and size variation

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  Venom composition of the Iberian adder (Vipera seoanei) from northern Portugal reveals limited sex and size variation Abstract Snake venom is a complex and dynamic ecological trait, with high potential for intraspecific variation. In this study, the venom composition of the Iberian adder ( Vipera seoanei ) from the Peneda Mountains of northern Portugal was investigated to explore whether venom varies with body size and sex. Venom proteomes from six individuals representing juvenile, subadult, and adult males and females were characterised using LC–MS/MS, while individual variation was assessed from SDS–PAGE profiles of 18 snakes. LC–MS/MS identified 144 proteins, dominated by phospholipases A 2 (PLA 2 ), snake venom serine proteases (svSP), and C-type lectin-related proteins (CTL). Descriptive comparisons revealed contrasting individual profiles, particularly between the juvenile male, characterised by high svSP and svMP abundance, and the juvenile female, characterised by high ...

Scorpion Sting: A Reason for Failed Local Anesthetic Action (CASE REPORT)

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Abstract

Failed action of local anesthetics can be due to technical errors, but resistance to local anesthetic agents can also be a reason. Scorpion venom has the potential to cause antibodies to local anesthetics and genetic mutations in the receptors resulting in local anesthesia resistance. We would like to report two cases with a history of scorpion stings in the past where resistance to local anesthetic agents was seen. Local anesthesia resistance can be manifested as inadequate block or block failure. In such cases, the anesthesiologist should keep a history of scorpion bite in mind in areas where scorpion sting is common. Eliciting the history of scorpion bites should be a part of the routine preoperative protocol in areas where scorpion bites are frequent.

Dalal KS, Chellam S, Toal PV, Panse S. Scorpion Sting: A Reason for Failed Local Anesthetic Action. Res Inno in Anesth 2023; 8 (2):57-59. 

https://www.riajournal.com/abstractArticleContentBrowse/JRIA/41/8/2/34782/abstractArticle/Article