Species diversity in the segmented spider genus Songthela (Mesothelae, Liphistiidae), with descriptions of 12 new species from Guizhou Province, China

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  Species diversity in the segmented spider genus Songthela (Mesothelae, Liphistiidae), with descriptions of 12 new species from Guizhou Province, China Abstract Twelve new species of the primitively segmented spider genus Songthela Ono, 2000, from Guizhou Province, China, are described based on the genital morphology of both sexes: S. chenjiapian sp. nov . (♂♀), S. cuantang sp. nov . (♂♀), S. fengxiang sp. nov . (♂♀), S. fuyan sp. nov . (♂♀), S. nanqiao sp. nov . (♂♀), S. parallela sp. nov . (♂♀), S. qingganglin sp. nov . (♂♀), S. tianba sp. nov . (♂♀), S. tudiao sp. nov . (♂♀), S. yanhe sp. nov . (♂♀), S. yinchiba sp. nov . (♂♀), and S. yuhu sp. nov . (♂♀). All new species are assigned to the multidentata -group based on the morphology of the male palp and female genitalia. Detailed diagnoses, descriptions, photographs, and a distribution map are provided. Mitochondrial cytochrome c oxidase subunit I ( COI ) sequences are also provided for the holotypes ...

Cytolytic Peptides from Oxyopes takobius Spider Venom Inhibit Chlamydial Growth

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Cytolytic Peptides from Oxyopes takobius Spider Venom Inhibit Chlamydial Growth

Abstract

Cytolytic peptides are a large, heterogeneous group of proteinaceous compounds capable of disrupting the integrity of biological membranes and causing cell lysis. Arthropod venom is a rich source of cytolytic peptides. Melittin from honeybee venom, as well as several peptides from the venom of the spider Lachesana tarabaevi, have previously been demonstrated to inhibit the growth of the intracellular parasitic bacterium Chlamydia trachomatis. In this study, using the Tet-On system for regulated gene expression in HEK293 cells, it was demonstrated that oxyopinins—cytolytic peptides derived from the venom of the spider Oxyopes takobius—exhibit similar anti-chlamydial activity. Oxyopinins have diverse amino acid sequences and are not homologous to previously studied peptides. This work significantly expands the range of known compounds with anti-chlamydial activity.

Polina, N., Kostryukova, E., Vassilevski, A. et al. Cytolytic Peptides from Oxyopes takobius Spider Venom Inhibit Chlamydial Growth. Biochem. Moscow Suppl. Ser. A 20, 343–348 (2026). https://doi.org/10.1134/S1990747826700200