Recent advances in venom pharmacology reshaping venom-to-drug discovery
Abstract
Animal venoms represent rich sources of pharmacologically active molecules, yet their translation into clinical therapeutics has historically progressed slowly. Recent advances in AI-driven venomics, cryo-electron microscopy, and computational peptide engineering are helping to overcome long-standing barriers in venom-based drug discovery and accelerate therapeutic translation.
Abd El-Aziz, T., De Waard, M., & Singh, B. (2026). Recent advances in venom pharmacology reshaping venom-to-drug discovery. Trends in Pharmacological Sciences. Advance online publication. https://doi.org/10.1016/j.tips.2026.06.006