Acute gonadal toxicity induced by Bothrops atrox venom in mice

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  Acute gonadal toxicity induced by Bothrops atrox venom in mice Abstract Bothrops atrox is responsible for most snakebite incidents in the Amazon region. Its venom is recognized for causing significant tissue damage and systemic effects. However, its effect on reproductive organs remains poorly explored. This study aimed to investigate the acute effects of B. atrox venom on testes and ovaries of adult mice. Male and female mice were exposed to B. atrox venom (½ LD 50 ) via four administration routes subcutaneous (SC), intramuscular (IM), intravenous (IV), and intraperitoneal (IP), followed by comprehensive assessment of gonadal histology, sperm function, oxidative stress biomarkers, antioxidant enzyme activities, and mRNA expression of inflammatory and apoptotic markers. Following B. atrox venom exposure, ovarian histological architecture remained preserved across all routes, whereas testicular tissue exhibited route-dependent injury ranging from moderate luminal apoptosis aft...

New considerations about the outstanding variability of the genus Chaerilobuthus Lourenço & Beigel, 2011 (Scorpiones: Chaerilobuthidae) and the description of one more new species from Early Cretaceous Burmite

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New considerations about the outstanding variability of the genus Chaerilobuthus Lourenço & Beigel, 2011 (Scorpiones: Chaerilobuthidae) and the description of one more new species from Early Cretaceous Burmite

Abstract

One more new species of fossil scorpion belonging to the genus Chaerilobuthus Lourenço & Beigel, 2011 is described from Early Cretaceous Burmite. Chaerilobuthus muelleri Lourenço sp. n., represents the 15th species to be described for this genus confirming therefore the strong speciose characteristic of this group. The new species shows several clear morphological differences when compared to the previous known species, attesting the existence of a major variability within Chaerilobuthus. A list of the known species is presented, as well a number of comments on the variability of different morphological characters.

Wilson R. Lourenço, Jürgen Velten. New considerations about the outstanding variability of the genus Chaerilobuthus Lourenço & Beigel, 2011 (Scorpiones: Chaerilobuthidae) and the description of one more new species from Early Cretaceous Burmite. Faunitaxys, 2026, 14 (11), pp.1-6. ⟨10.57800/faunitaxys-14(11)⟩. ⟨hal-05528828⟩