Can Scorpion Venom Peptides Be Safely Used in Cardiovascular Therapy: A Systematic Review

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  Can Scorpion Venom Peptides Be Safely Used in Cardiovascular Therapy: A Systematic Review Abstract Scorpion venom contains numerous bioactive peptides with potent cardiovascular effects, including bradykinin-potentiating peptides (BPPs), ion channel modulators, and cardioprotective molecules. These peptides show promise for conditions such as hypertension, cardiac injury, and arrhythmias. However, concerns regarding toxicity, immunogenicity, and off-target actions have limited their clinical development. This systematic review evaluates the therapeutic potential and safety of scorpion venom peptides for cardiovascular applications. A systematic search of PubMed, Scopus, Google Scholar, and Semantic Scholar identified 1,141 articles. Screening of 463 abstracts and full-text review of 446 eligible studies resulted in 17 publications meeting the inclusion criteria. Extracted data included mechanisms, efficacy, toxicity, and translational challenges. BPPs consistently demonstrated AC...

First record of Tropicosa thorelli (Araneae: Lycosidae) attacking the dragonfly Rhionaeschna marchali (Odonata: Aeshnidae)

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First record of Tropicosa thorelli (Araneae: Lycosidae) attacking the dragonfly Rhionaeschna marchali (Odonata: Aeshnidae)

Abstract 

This study records thirteen predation attempts by the wolf spider Tropicosa thorelli (Keyserling) on males of the aeshnid dragonfly Rhionaeschna marchali (Rambur) in a protected area of the Colombian Andes. All events occurred on macrophyte vegetation near the shoreline of the Tominé Reservoir, at the locality of Club Náutico El Muña. For each event, we recorded perch height, time of occurrence, attack duration, and ambient temperature. The observations took place between 11:01 and 11:47 h during the dry season, under temperatures ranging from 21.2 to 23.7 °C. The mean duration of attack events was 12.72 ± 2.41 min. In all cases, the attacks were interrupted by the arrival of R. marchali males, although the mechanisms underlying this behavior remain unclear. These observations suggest that perch characteristics, particularly perch height, may influence the vulnerability of R. marchali males to predation by sit-and-wait spiders. 

Palacino Rodríguez, F., & Palacino-Penagos, D. A. (2026). Primer registro de Tropicosa thorelli (Araneae: Lycosidae) atacando a la libélula Rhionaeschna marchali (Odonata: Aeshnidae). Biota Colombiana, 27, e1300. https://doi.org/10.21068/2539200X.1300