Sulfated Fucosyl-Guanosines: Understudied Compounds from Spider Venom

 

Sulfated Fucosyl-Guanosines: Understudied Compounds from Spider Venom

Abstract

Low molecular mass compounds are the least understood among the components of spider venom. Sulfated fucosyl-guanosines originally detected from Hololena curta McCook are unique and rarely found in nature. While their synthetic counterparts are widely used as antibiotics. The present work compiles the current knowledge of these molecules, exploring their potential biogenetic origin. Additional topics highlight biochemistry and their significance as natural products with potential for pharmaceutical developments.

Carvajal, M. A., & Victor Fajardo, M. (2026). Sulfated Fucosyl-Guanosines: Understudied Compounds from Spider Venom. Toxicon, 109033. https://doi.org/10.1016/j.toxicon.2026.109033