Investigating the therapeutic role of Leuculectin, a C-type lectin from Bothrops leucurus snake venom, in corneal neovascularization

Posted by
  Investigating the therapeutic role of Leuculectin, a C-type lectin from Bothrops leucurus snake venom, in corneal neovascularization Abstract Pathological corneal neovascularization remains a major therapeutic challenge due to the limited efficacy and safety of currently available antiangiogenic treatments. Although C-type lectins from snake venom possess various biological activities, their potential to modulate pathological ocular angiogenesis has not been explored. This study investigated the antiangiogenic effects of Leuculectin, a C-type lectin isolated from Bothrops leucurus venom using an experimental model of corneal neovascularization (CNV), a HUVEC (human umbilical vein endothelial cell) tube formation assay, and the chick embryo chorioallantoic membrane (CAM) assay. In the HUVEC tube formation assay, Leuculectin demonstrated strong antiangiogenic activity. In the CAM assay, Leuculectin applied at concentrations of 1.5, 2.5 and 3.5 μg/mL significantly decreased new ves...

On the genus Catumiri Guadanucci, 2004 (Araneae: Theraphosidae) in Chile, with description of a new species

Posted by

 


On the genus Catumiri Guadanucci, 2004 (Araneae: Theraphosidae) in Chile, with description of a new species

Abstract
A new species of tarantula, belonging to the genus Catumiri from Chile is described. Catumiri almonacidae sp. nov. presents unique characteristics in the male palpal bulb and tibial apophysis, and the female spermathecae. It is distributed in the south centre of Chile, between 33.5° S and 35.4° S latitude. This species is commonly known in Chile informally as the Mahogany Dwarf Tarantula. The new species is diagnosed, described and illustrated. Comments on the natural history and a distribution map of the genus are presented.

Montenegro, Rubén & Aguilera, Milenko. (2025). ON THE GENUS CATUMIRI GUADANUCCI, 2004 (ARANEAE: THERAPHOSIDAE) IN CHILE, WITH DESCRIPTION OF A NEW SPECIES. 47. 82-86.