Role of snake venom proteases and tissue factor in venom induced hemostatic disorders and local hemorrhage in mice

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  Role of snake venom proteases and tissue factor in venom induced hemostatic disorders and local hemorrhage in mice Abstract Bothrops jararaca venom (BjV) induces hemostatic and inflammatory manifestations. Tissue factor (TF) is essential for hemostasis, but aberrant TF expression can cause coagulopathy. We determined the effect of inhibition of BjV serine proteases and metalloproteinases, as well as host TF, on the systemic coagulopathy and local hemorrhage in envenomed mice. Venom serine proteases induced hypofibrinogenemia whereas venom metalloproteinases induced hemorrhage. TF did not contribute to venom-induced coagulopathy, but played a protective role in venom-induced bleeding in mice. Sachetto, A. T., Mackman, N., & Santoro, M. L. (2026). Role of snake venom proteases and tissue factor in venom induced hemostatic disorders and local hemorrhage in mice. Toxicon , 109299. https://doi.org/10.1016/j.toxicon.2026.109299

A new species of Reversopelma Schmidt, 2001 from Ecuador, and two new tarantula genera from Argentina, Bolivia, and Colombia (Araneae: Theraphosidae)

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A new species of Reversopelma Schmidt, 2001 from Ecuador, and two new tarantula genera from Argentina, Bolivia, and Colombia (Araneae: Theraphosidae)

Abstract
The genus Reversopelma Schmidt, 2001 is revised and diagnosed based on examination of the type material of its type species, R. petersi Schmidt, 2001, and a new species, Reversopelma spinometatarsi sp. nov., from Ecuador. The new species from Ecuador provides further knowledge on the male palpal bulb and spermathecal morphology of Reversopelma, supporting the delimitation of a new genus: Vitriemboli gen. nov. (type species Vitriemboli diaguita sp. nov.), easily distinguished from Reversopelma by the presence of urticating setae types III and IV. The Bolivian species Reversopelma herzogi Gabriel, Sherwood & Pérez-Miles, 2023 is transferred to Vitriemboli (Vitriemboli herzogi comb. nov.) based on urticating setae and male palpal bulb morphology. A second new genus, Colombiarachne gen. nov. (type species Colombiarachne dianae sp. nov.), discovered separately, is described from Colombia.

Peñaherrera-R, Pedro & Guerrero-Campoverde, Ariel & León-E, Roberto J. & Ríos Tamayo, Duniesky & Sherwood, Danniella & Cisneros-Heredia, Diego. (2025). A new species of Reversopelma Schmidt, 2001 from Ecuador, and two new tarantula genera from Argentina, Bolivia, and Colombia (Araneae: Theraphosidae). Arachnology. 20. 462-472.