Snake Venom and Antivenom Pharmacology

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  SNAKE VENOM & ANTIVENOM Chemistry, Composition, Mechanisms and Pharmacology Abstract This integrated teaching session for Phase III MBBS students focused on the pharmacology and toxicology of snake venom and the principles of antivenom therapy. The lecture covered the chemistry, composition, mechanisms of action, and pharmacological effects of snake venoms and antivenoms. Rational use of antivenoms, indications, administration protocols, adverse reactions, and supportive management strategies were discussed. The session also highlighted the translational importance of venom-derived compounds in modern drug development. Recent advances in antivenom research, including recombinant human monoclonal antibodies, toxin-specific inhibitors, synthetic antibody technologies, and next-generation broad-spectrum antivenoms, were reviewed. Current discoveries and emerging approaches aimed at improving efficacy, safety, affordability, and accessibility of antivenom therapy were also explor...

The genome sequence of the spider-hunting wasp, Priocnemis perturbator (Harris, 1780) (Hymenoptera: Pompilidae)

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The genome sequence of the spider-hunting wasp, Priocnemis perturbator (Harris, 1780) (Hymenoptera: Pompilidae)

Abstract

We present a genome assembly from an individual female Priocnemis perturbator (spider-hunting wasp; Arthropoda; Insecta; Hymenoptera; Pompilidae). The genome sequence has a total length of 391.62 megabases. Most of the assembly (67.88%) is scaffolded into 15 chromosomal pseudomolecules. The mitochondrial genome has also been assembled, with a length of 28.93 kilobases. Gene annotation of this assembly on Ensembl identified 24 581 protein-coding genes. This assembly was generated as part of the Darwin Tree of Life project, which produces reference genomes for eukaryotic species found in Britain and Ireland.

Crowley LM, University of Oxford and Wytham Woods Genome Acquisition Lab, Darwin Tree of Life Barcoding Collective et al. The genome sequence of the spider-hunting wasp, Priocnemis perturbator (Harris, 1780) (Hymenoptera: Pompilidae) [version 1; peer review: awaiting peer review]. Wellcome Open Res 2025, 10:599 (https://doi.org/10.12688/wellcomeopenres.25074.1)