First chance to see: New jumping-spider species from Batanta, Indonesia (Araneae, Salticidae, Euophryini)

  First chance to see: New jumping-spider species from Batanta, Indonesia (Araneae, Salticidae, Euophryini) Abstract The first spider records of Batanta, Birie, and Arefi islands, Raja Ampat, Indonesia are presented in this study. Three new species in the genus Canama Simon, 1903, Canama horobi sp. nov . (male), Canama limagigi sp. nov . (male) and Canama wanita sp. nov . (female) are described. Two Indonesian salticids, originally placed in Bathippus Thorell, 1892 and known from their original descriptions only, Bathippus dentiferellus Strand, 1911 and Bathippus seltuttensis Strand, 1911, are redescribed and illustrated. Due to their morphological similarity to the type species, three new combinations have been proposed: Canama dentiferellus (Strand, 1911), comb. nov ., Canama seltuttensis (Strand, 1911), comb. nov . and Canama dilanians (Thorell, 1881), comb. nov . To confirm the phylogenetic placement of the new species, we carried out a small phylogenetic anal...

Targeted Metabolomics of Tityus Scorpion Venoms: Unveiling Small-Molecule Components

 


Targeted Metabolomics of Tityus Scorpion Venoms: Unveiling Small-Molecule Components

Abstract

Scorpion venoms consist of proteins, peptides, and various low molecular weight (LMW) organic compounds, which act as toxins. Despite their potential significance, these compounds in scorpion venoms have been little investigated and their full range has not been well characterized. In this work, a targeted metabolomic approach was used in combination with an HPLC-QTOF-MS methodology to create a library of 55 LMW standard compounds, for the analysis of venoms from three Tityus species scorpions. This strategy enabled reliable identification of 45 compounds, including 20 amino acids, 4 organic acids, 12 biogenic amines, 6 nitrogenated bases and derivatives, 2 β-carboline-derived alkaloids, and 1 amphetamine. Most of the compounds identified were neurotransmitters and/or neurotoxins, while others can act as homeostasis disruptors or affect the diffusion of venom through the bodies of victims. Therefore, the LMW organic compounds in scorpion venoms play roles in the killing or paralyzing of prey, as well as in defense against large predators.

Targeted Metabolomics of Tityus Scorpion Venoms: Unveiling Small-Molecule Components
Nathalia Baptista Dias, Bibiana Monson de Souza, Geovanny Barroso, Javier Ortiz Leiva, Gabriela Mendonça Paula, Hipócrates M. Chalkidis, Valquíria Abrão Coronado Dorce, Osmar Malaspina, and Mario Sergio Palma, Journal of the American Society for Mass Spectrometry Article ASAP
DOI: 10.1021/jasms.5c00238