Associations Between Snakebite Severity Scores and Antivenin Administration

Posted by

Fab or F(ab’)2 Antivenom: Which Should we use for North American Crotalids?

Posted by

 


Fab or F(ab’)2 Antivenom: Which Should we use for North American Crotalids?

We read with interest a pair of articles comparing different aspects of Crotalidae polyvalent immune Fab (CroFab®, BTG International) or Crotalidae immune F(ab’)2(Anavip®, Rare Disease Therapeutics),the two principle antivenoms (AV) for North American pit viper envenomations [1, 2]. Both articles employed the Toxicology Investigators Consortium (ToxIC) North American Snake Bite Registry (NASBR), and both articles sought to determine whether one antivenom is preferable to the other. The two articles point to different answers to the question, “Which antivenom should our hospital use?”

McKnight, M., Mullins, M.E. Fab or F(ab’)2 Antivenom: Which Should we use for North American Crotalids?. J. Med. Toxicol. (2025). https://doi.org/10.1007/s13181-025-01098-1