Molecular Recognition and Immunopharmacological Implications of Serratiopeptidase Targeting Snake Venom Bradykinin-Potentiating Peptides

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  Molecular Recognition and Immunopharmacological Implications of Serratiopeptidase Targeting Snake Venom Bradykinin-Potentiating Peptides Abstract Purpose Bradykinin-potentiating peptides (BPPs), found in snake venom, are known to modulate cardiovascular functions, but their susceptibility to enzymatic degradation remains poorly understood. Methods Models were generated using AlphaFold-Colab for five small BPPs (< 9 amino acids) that did not have experimentally solved structures, and those BPPs which had reliable predictions of structure (pLDDT > 80) were used for docking studies. Protein-peptide docking experiments were done using HADDOCK for studying the interaction between wild-type (WT) and mutant serratiopeptidase with BPPs. After selecting the best complex, simulation of the complex was done using molecular dynamics (MD) simulations for 100 ns and binding energy determination using MM/PBSA analysis. For checking the mechanical stability of the protein-peptide complexes...

Cloud forest scorpions: a new species of Guyanochactas Lourenço, 1998 (Scorpiones, Chactidae) from Mount Itoupé in French Guiana

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Cloud forest scorpions: a new species of Guyanochactas Lourenço, 1998 (Scorpiones, Chactidae) from Mount Itoupé in French Guiana

Abstract. – 

A new species of scorpion belonging to the genus Guyanochactas Lourenço, 1998 (family Chactidae Pocock, 1893), is described on the basis of one specimen collected in the cloud forest of Mount Itoupé, the second highest peak of French Guiana. Guyanochactas itoupe sp. n. represents the fourth species of the genus reported from French Guiana and the total number of Guyanochactas species is now raised to six. The new species is a possible vicariant of Guyanochactas touroulti Lourenço, 2018, equally described from a massif formation of French Guiana, the Mitaraka.

Ythier E., Chevalier J. & Lourenço W. R., 2025. – Scorpions des forêts de nuages : une nouvelle espèce de Guyanochactas Lourenço, 1998 (Scorpiones, Chactidae) du Mont Itoupé en Guyane Française. Faunitaxys, 13(48): 1 – 9. https://archive.org/details/faunitaxys-f-386