Ecological and social contexts of scorpion stings in Manaus, the largest metropolis of the Brazilian Amazon

  Ecological and social contexts of scorpion stings in Manaus, the largest metropolis of the Brazilian Amazon Abstract Scorpion stings remain a significant public health problem in tropical regions, particularly in Brazil, where an estimatied 117,185 cases are reported annually, reflecting a persistent and growing burden on the healthcare system. Globally, more than two million cases occur each year, especially in areas undergoing environmental disturbances such as deforestation and unplanned urbanization. This study investigates the ecological and social contexts of scorpion stings in Manaus, the largest metropolis of the Brazilian Amazon. This qualitative study was conducted at the Dr. Heitor Vieira Dourado Tropical Medicine Foundation (FMT-HVD), a reference center for scorpion stings, between January 2020 and March 2025. Data were collected through clinical questionnaires, in-depth interviews, and household field observations. Thematic analysis was performed using Atlas.ti. Thir...

Neurotoxic effects of scorpion envenomation, a video of nystagmus, dysmetria, and tongue fasciculations: a case report

 


Neurotoxic effects of scorpion envenomation, a video of nystagmus, dysmetria, and tongue fasciculations: a case report

Abstract

Background

Scorpion stings are common in rural areas worldwide, with most cases being benign. However, certain species, such as Centruroides in Southwestern USA, can cause severe neurotoxic envenomations. Neurotoxic symptoms, including nystagmus and ataxia, are well documented in pediatric cases but remain rare in adults. We present a rare case of neurotoxic scorpion envenomation in an adult.

Case presentation

A 32-year-old Hispanic female with a history of anaphylaxis to bee venom presented to the emergency department (ED) following a scorpion sting. While sitting at home, she felt two stings on her posterior right thigh, identified and killed the scorpion, and went to the ED. On evaluation, the patient was alert and oriented (Glasgow Coma Scale score of 15). Her vital signs were stable, and laboratory results were unremarkable. The patient initially experienced localized pain at the sting site, followed by generalized heaviness, muscle twitching, dry mouth, tongue “fuzziness,” and throat heaviness but no respiratory distress. Neurological examination revealed nystagmus, tongue fasciculations, and dysmetria, consistent with neurotoxic envenomation. She was treated with a tetanus–diphtheria–pertussis (Tdap) booster, normal saline, ondansetron, lorazepam, and Centruroides scorpion antivenom (ANASCORP®). Owing to her anaphylaxis history, she was closely monitored for hypersensitivity reactions. The patient had an uneventful recovery and was discharged after 2 days without neurological complications.

Conclusion

Scorpion envenomations can lead to severe neurotoxic effects, even in adults, particularly with multiple stings or enhanced venom absorption. Early recognition of neurotoxic symptoms is crucial for prompt intervention with antivenom and supportive care, significantly improving patient outcomes. This case emphasizes the importance of considering neurotoxic envenomations in adult patients, even when pediatric cases are more common.



Mohammed, S., Herrera, E.R. & Kioka, M. Neurotoxic effects of scorpion envenomation, a video of nystagmus, dysmetria, and tongue fasciculations: a case report. J Med Case Reports 19, 362 (2025). https://doi.org/10.1186/s13256-025-05416-7