Structural and functional characterisation of isolated puff adder (Bitis arietans) venom serine proteases

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  Structural and functional characterisation of isolated puff adder (Bitis arietans) venom serine proteases Abstract Serine proteases (SVSPs) are known to play a major role in the haemotoxic actions of viper venom, but compared with those from other medically important vipers, the serine proteases of puff adder venoms have not been extensively characterised. To address this, we isolated, identified and characterised the bioactivity of the serine proteases within the venom of the Nigerian puff adder, which we had previously shown to be especially rich in this class of toxin. Two distinct groups were identified, each with different protein substrate specificities. Both had similar molecular weights of 52-62 kDa, with 4-6 N-glycans, but one group consisted of trypsin-like acidic SVSPs and the other of non-trypsin-like basic SVSPs with a specificity for aliphatic amino acids at the P 1 position. Each acted differently on fibrinogen: the acidic SVSPs showed thrombin-like alpha/beta-fib...

The scorpions of the Estación de Biología Chamela, Jalisco, Mexico with the description of a new species of Mesomexovis (Scorpiones, Vaejovidae) and an identification key

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The scorpions of the Estación de Biología Chamela, Jalisco, Mexico with the description of a new species of Mesomexovis (Scorpiones, Vaejovidae) and an identification key

Abstract

Mesomexovis Gonzalez-Santillan & Prendini, 2013 is a scorpion genus of the Vaejovidae family that comprises seven species, all endemic to Mexico. The present study describes a new species from Estación de Biología Chamela, Jalisco, related to M. occidentalis (Hoffmann, 1931), M. atenango (Francke & Gonzalez-Santillan, 2006), and M. subcristatus (Pocock, 1898). Mesomexovis caxcan sp. nov. differs from these species in several respects. Firstly, the carinae of the pedipalp chelae are vestigial. Secondly, the ventral lateral carinae of metasomal segments I–IV are granular, and the ventral submedian carinae of segments I–IV are costate to granular. A microstructural separation between the subex and the basal carina of the capsular area of the hemispermatophore is described for the first time. Mesomexovis caxcan sp. nov. represents the eighth species of the genus and the fifth reported in the Estación de Biología Chamela. The other scorpions identified in this location are Centruroides chamela Ponce-Saavedra & Francke, 2011, C. elegans (Thorell, 1876) (Buthidae), Konetontli chamelaensis (Williams, 1986), and Thorellius intrepidus (Thorell, 1876) (Vaejovidae).

de Araujo Lira AF, González-Santillán E (2025) The scorpions of the Estación de Biología Chamela, Jalisco, Mexico with the description of a new species of Mesomexovis (Scorpiones, Vaejovidae) and an identification key. ZooKeys 1243: 241-267. https://doi.org/10.3897/zookeys.1243.146978