Cicileus derradji sp. nov., a new species from southern Algeria (Scorpiones: Buthidae)

  Cicileus derradji sp. nov., a new species from southern Algeria (Scorpiones: Buthidae) Abstract A new scorpion species, Cicileus derradji sp. nov., is described from Tin Zaouatine District, In Guezzam Province, southern Algeria. The description is based on an adult male holotype, an adult female paratype and a juvenile specimen, and is supported by detailed morphological analyses, including colouration, morphometrics, carination patterns and trichobothrial arrangement. This discovery extends the known distribution of the genus Cicileus approximately 500 km southwestward within Algeria. With the addition of this species, the number of recognised species in the genus increases to six. The new species is compared with all previously known species of Cicileus , and detailed colour photographs, including images taken under ultraviolet illumination, are provided. Derradj, L., Aydın Yağmur, E., Benali, N., & Bikada, M. (2026). Cicileus derradji sp. nov., a new species from south...

Transcriptomics-Informed Proteomics of Venom Glands and Crude Venom from Tityus cf. Asthenes from Panama: Enzymes, Proteins, Toxins, and Antimicrobial Peptides

 


Transcriptomics-Informed Proteomics of Venom Glands and Crude Venom from Tityus cf. Asthenes from Panama: Enzymes, Proteins, Toxins, and Antimicrobial Peptides

Abstract

The venom gland and the crude venom of Tityus cf. asthenes were analyzed by transcriptomic and proteomic methods. High-throughput RNA sequencing (RNA-seq) and mass spectrometry (MS/MS) allowed for the identification of a wide range of venom proteins. Notably, transcriptomic and proteomic venom approaches identified a hyaluronidase, toxins that affect the voltage-gated Na+ channels, LVPs, cysteine-rich secretory proteins, metalloproteinases, serine proteases, alpha-amylases, toxins that affect the voltage-gated K+ channel, scorpion calcin-like, single insulin-like growth factor-binding domain proteins, nondisulfide-bridged peptides, lectins, chitinases, Kunitz-type serine protease inhibitors, cyclotide trypsin inhibitors, and uncharacterized proteins. These newly identified components enhance the understanding of the venomous nature of Tityus cf. asthenes.


Transcriptomics-Informed Proteomics of Venom Glands and Crude Venom from Tityus cf. Asthenes from Panama: Enzymes, Proteins, Toxins, and Antimicrobial Peptides
Marcos H. Salazar, Octavio Samudio, Iván Arenas, Magdalena Hernández-Ortiz, Herlinda Clement, Lorena Hernandez-Orihuela, Sergio Encarnación-Guevara, John Cleghorn, Hildaura Acosta, and Gerardo Corzo, Journal of Proteome Research Article ASAP