Scorpion Venom Peptides: From Structural Scaffolds to Therapeutic Applications—A Focus on Antioxidant Mechanisms and Translational Perspectives

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  Scorpion Venom Peptides: From Structural Scaffolds to Therapeutic Applications—A Focus on Antioxidant Mechanisms and Translational Perspectives Abstract Scorpion venom peptides, with their stable disulfide backbone, compact structural framework, and highly selective regulation of ion channels, have long been regarded as important molecular probes in neuropharmacology. However, recent studies have revealed their potential for regulating oxidative stress, inflammation, and neuroprotection, making them a new research frontier. In this article, we focus on scorpion venom peptides as drugs, constructing an integrated knowledge framework from structural classification to clinical translation. First, scorpion venom peptides are systematically classified based on cysteine arrangement patterns and three-dimensional folding topology, and their structure–activity relationships are summarized. Based on this, the molecular mechanisms by which scorpion venom peptides regulate ion channels are ...

A new species of Conothele Thorell, 1878 (Araneae: Halonoproctidae) from the western Himalayas, India

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A new species of Conothele Thorell, 1878 (Araneae: Halonoproctidae) from the western Himalayas, India

Abstract
A new species of trapdoor spider, Conothele mussoorie sp. nov., is described from the foothills of the Himalayas, marking the first record of this genus from the northernmost part of India. Detailed descriptions and illustrations of the female are provided.

Tripathi, Rishikesh & Kadam, Gautam. (2025). A new species of Conothele Thorell, 1878 (Araneae: Halonoproctidae) from the western Himalayas, India. Arachnology. 20. 76-79.