Barietin, a snake venom vascular endothelial growth factor from puff adder Bitis arietans venom, increases the heart rate with minor effect on blood pressure in rats

Posted by
  Barietin, a snake venom vascular endothelial growth factor from puff adder Bitis arietans venom, increases the heart rate with minor effect on blood pressure in rats ABSTRACT Snake venom vascular endothelial growth factors (svVEGFs) are homodimeric proteins comprising two equal subunits bound by two intermolecular disulfide bonds. The main biological effects of svVEGFs are local vasodilatation, increasing of vascular permeability, and hypotension. Barietin, a svVEGF purified from the venom of puff adder Bitis arietans , differs from other representatives of this toxin family by its shortened C-terminal amino acid sequence. No data about barietin effects on hemodynamics are available. Studying those in rats we found that barietin at a dose of 1 mg/kg significantly increased heart rate, exerting only a minor influence on blood pressure. In this respect, it differs from other svVEGFs having a significant effect on blood pressure. We aimed to find the barietin active fragment which m...

On Antillean ochyroceratines (Scytodoidea: Ochyroceratidae: Ochyroceratinae), with the description of three new species from Cuba

Posted by

 


On Antillean ochyroceratines (Scytodoidea: Ochyroceratidae: Ochyroceratinae), with the description of three new species from Cuba

Abstract

Ochyroceratinae is a diverse subfamily that has received fragmentary taxonomic attention. We here present a survey of Cuban species belonging to this group and examine the results in the light of recent phylogenies of the family. Three new species belonging to Ochyrocera Simon, 1892, are named: Ochyrocera luisarmasi sp. nov., O. maestra sp. nov. and O. mayabeque sp. nov. The new species are close relatives of the type species of Fageicera Dumitrescu & Georgescu, 1992, but some of them lack the diagnostic characters of the genus, blurring the limits between these genera. In addition, Fageicera nests phylogenetically within Ochyrocera. At the same time, we find no support to maintain the fossil genus †Arachnolithulus Wunderlich, 1988 (from Dominican amber) as a different taxon from extant Ochyrocera. Thus, we here propose Fageicera and †Arachnolithulus as syn. nov. of Ochyrocera, resulting in the following new combinations: †Ochyrocera longipes (Wunderlich) comb. nov., †O. pygmaeus (Wunderlich) comb. nov., O. cubana (Dumitrescu & Georgescu) comb. nov., O. loma (Dumitrescu & Georgescu) comb. nov., O. matarredondensis (Cuervo & Buitrago) comb. nov., and O. nasuta (Dumitrescu & Georgescu) comb. nov. Additionally, we argue that Ochyrocera Simon, 1892 nomen protectum, which is in prevailing usage, has an older synonym, Pandeus Keyserling, 1891 nomen oblitum, but Simon’s name qualifies for a reversal of precedence and should be retained as valid following Article 23.9 of the International Code of Zoological Nomenclature.

Pérez González, Abel & Magalhaes, Ivan. (2025). On Antillean ochyroceratines (Scytodoidea: Ochyroceratidae: Ochyroceratinae), with the description of three new species from Cuba. 
Zootaxa. 5563. 264-289. 10.11646/zootaxa.5563.1.18.