Antitumor activity of scorpion venom-derived peptides: A meta-analysis of preclinical studies

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  Antitumor activity of scorpion venom-derived peptides: A meta-analysis of preclinical studies Abstract Despite advances in cancer therapeutics, there are still challenges in improving drug toxicity and selectivity. Peptides from various venous species have recently garnered attention for their biopharmaceutical potential, particularly in cancer. The present study aimed to conduct a meta-analysis of the antitumor activity of scorpion venom-derived peptides (SVDPs) previously reported in preclinical models. The bibliographic research included original and review articles written in English published from 2015 to 2026. Studies within the scope were retrieved from the EBSCO Discovery Service, PubMed, and WIPO databases. A total of 27 articles that met the inclusion and exclusion criteria were included in this research, and the collected data were synthesized through a meta-analysis. In the included in vitro and in vivo studies, the effect of SVDPs on breast/mammary gland, cervical,...

A new species of Vitalius (Araneae: Theraphosidae) from the Brazilian Cerrado

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A new species of Vitalius (Araneae: Theraphosidae) from the Brazilian Cerrado

Abstract

A new theraphosid species, Vitalius ornatissimus sp. nov., is described based on one male and one female from Brazil. The new species is distributed in the Brazilian states of Tocantins, Goiás, Distrito Federal, and the western state of Bahia, living in areas of the Cerrado biome. It is closely related to and resembles Vitalius chromatus (Schmidt, 2004) in appearance, with a general black coloration and whitish rings or stripes on the legs and palp in both sexes. With V. chromatus, it shares the presence of a row of spines on the distal-retrolateral edge of palpal tibia of male, but differs by the tibial apophysis and metatarsus I shape. Vitalius ornatissimus sp. nov. is the first species of Vitalius Lucas, Silva Jr & Bertani recorded exclusively in central Cerrado.

Bertani, R., & Motta, P. C.. (2024). A new species of Vitalius (Araneae: Theraphosidae) from the Brazilian Cerrado. Zoologia (curitiba), 41, e24011. https://doi.org/10.1590/S1984-4689.v41.e24011