Notes on the identity of the orb-weaver spider Araneus nox Simon, 1877 (Araneae: Araneidae) from India, including its transfer to Eriovixia Archer, 1951 and one new synonymy

  Notes on the identity of the orb-weaver spider Araneus nox Simon, 1877 (Araneae: Araneidae) from India, including its transfer to Eriovixia Archer, 1951 and one new synonymy The orb-weaver genus Araneus Clerck, 1757 has historically served as a heterogeneous assemblage for numerous araneid spiders lacking clear generic placement, and several Asian species formerly assigned to Araneus have subsequently been transferred to more narrowly defined genera. One species that still needs further investigation on its true identity is Araneus nox (Simon, 1877), originally described as Epeira nox Simon, 1877 from Basilan Island, Philippines, and later transferred to Araneus by Simon (1905). In the same year as the description of Epeira nox, Thorell (1877) described Epeira pilula from the Moluccas (Indonesia), which was subsequently synonymised under Epeira nox by Simon (1880). Despite its broad Oriental distribution, the taxonomic identity and generic placement of A. nox have remained insuff...

Proteomic analysis of two novel peptides from the Odontobuthus doriae scorpion venom

 


Proteomic analysis of two novel peptides from the Odontobuthus doriae scorpion venom

Abstract

The venom of the Odontobuthus doriae scorpion, prevalent in East Asia and Iran, has not been fully characterized. This study provides the first proteomic profile of O. doriae venom to explore its potential as a medical. 2D-PAGE analysis revealed 96 protein spots with isoelectric points from 3 to 9 and molecular weights between 6.6 to 205 kDa. Fourteen toxin fractions were isolated via HPLC, and SDS-PAGE showed seven protein bands ranging from 3.8 to 182 kDa. MALDI-TOF MS identified Peptide 1 and Peptide 2, resembling Hemoglobin beta-2 chain and Chaperonin HSP60 and suggest potential therapeutic applications for P1 and P2.

Zargan, J., Jahangirian, E., Khan, H. A., & Ali, S. (2024). Proteomic analysis of two novel peptides from the Odontobuthus doriae scorpion venom. Journal of Asian Natural Products Research, 1–22. https://doi.org/10.1080/10286020.2024.2403612