Post-traumatic phenomena secondary to snakebite envenomation: a psychiatric clinical perspective

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  Post-traumatic phenomena secondary to snakebite envenomation: a psychiatric clinical perspective Abstract Snakebite envenomation represents a major global public health concern. Beyond physical outcomes suffered by the patients, studies have documented significant psychiatric and psychological sequelae. Consequently, there is an urgent need to document and intervene the psychiatric/psychological sequelae of snakebite envenomation alongside the clinical assessment. This work presents a narrative review of the psychiatric consequences described in snakebites in several settings. In addition, it addresses the screening/detection actions focused on Post-Traumatic Phenomena from a psychiatric perspective that are useful in general and specialized medicine settings in snakebite envenomation. Millán-González, R., & Gutiérrez, J. M. (2026). Post-traumatic phenomena secondary to snakebite envenomation: A psychiatric clinical perspective. Toxicon , 109117. https://doi.org/10.1016/j.tox...

Behavioral, biochemical and histopathological alterations induced in Swiss mice by Buthus boumalenii scorpion venom

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Behavioral, biochemical and histopathological alterations induced in Swiss mice by Buthus boumalenii scorpion venom


Abstract

The yellow scorpion, Buthus boumalenii, has long been recognized as a potentially dangerous species endemic to Morocco. However, there is currently no data on the in vivo toxicity or effects of Buthus boumalenii venom, as it has not been studied to the best of our knowledge. In order to achieve the objective of this study, the LD50 of B. boumalenii venom will be initially calculated, followed by determining its impact on vital organs using histological, biochemical, and behavioral analyses. The investigation also explores potential neurobehavioral impairments in Swiss mice at intervals of 3 hours, 6 hours, and 12 hours post-envenomation. The LD50 for Buthus boumalenii scorpion venom in mice was determined to be 353 µg/kg based on body weight. The findings of the study highlight the potential lethality of B. boumalenii. Observations related to the poisoning provide indications of potential tissue damage in specific vital organs. To sum up, the venom from this scorpion has the potential to result in considerable medical complications, including fatalities, particularly in individuals at risk. Consequently, healthcare practitioners should be knowledgeable about the diverse scorpion species in their regions and adhere to contemporary medical protocols when addressing scorpion envenomation.


Ettitaou, A. et al. (2024) ‘Behavioral, biochemical and histopathological alterations induced in Swiss mice by Buthus boumalenii scorpion venom’, Toxin Reviews, pp. 1–14. doi: 10.1080/15569543.2024.2346164.