Description of a new species of Zodarion Walckenaer (Araneae: Zodariidae) from Turkey

  Description of a new species of Zodarion Walckenaer (Araneae: Zodariidae) from Turkey Introduction Zodariidae Thorell, commonly known as ant-eating spiders, is one of the most diverse spider families, comprising over 1300 species across 90 genera (World Spider Catalog  Citation 2026 ). Members of the family are distributed worldwide, mostly in tropical and subtropical regions (World Spider Catalog  Citation 2026 ). Within this large family, the genus Zodarion Walckenaer, is represented by 176 species (World Spider Catalog  Citation 2026 ). Currently, 157 Zodarion species are known from Europe (Nentwig et al .  Citation 2026 ). In Turkey, the family Zodariidae comprises 37 species in four genera. Most of them, 34 species, belong to the genus Zodarion (Danışman et al. ,  Citation 2025 ). Within the genus, eight species of the ‘ germanicum ’ species group are found in Turkey: Zodarion abantense Wunderlich, Z. bigaense Bosmans, Özkütük, Varlı, and Kunt, ...

A Structure-Informed Atlas of Venom-Derived Peptides Reveals the Organization of Chemical Space

 

A Structure-Informed Atlas of Venom-Derived Peptides Reveals the Organization of Chemical Space

Abstract

Venom-derived peptides are structurally diverse bioactive scaffolds with growing relevance for computational discovery and molecular design. However, their organization within chemical space remains poorly characterized in integrated frameworks. Here, we present a curated, structure-informed venom peptide atlas supported by an integrated descriptor-based framework combining sequence- and structure-derived features across 3,423 peptides. High-confidence AlphaFold models were integrated with physicochemical and structural descriptors to generate a unified molecular representation. Multivariate analyses reveal that venom peptides occupy constrained and interpretable regions of chemical space shaped by disulfide-mediated stabilization, structural compactness, and electrostatic–hydrophobic balance. Functional classes show clear separation, whereas taxonomic origin explains less variance, supporting convergent design principles. This atlas provides a reference resource for comparative analyses, scaffold prioritization, and hypothesis generation in peptide science.

Gonçalves, T. C., Toral Cortez, E. H., & Amaral, D. T. (2026). A Structure-Informed Atlas of Venom-Derived Peptides Reveals the Organization of Chemical Space. Molecular Informatics, 45(5), e70039. https://doi.org/10.1002/minf.70039