Distributional Notes on Three Wolf Spider Species (Araneae: Lycosidae) Recorded for the First Time in Diyala Province, Iraq

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  Distributional Notes on Three Wolf Spider Species (Araneae: Lycosidae) Recorded for the First Time in Diyala Province, Iraq Abstract This study presents new distributional data for three wolf spider species (Araneae: Lycosidae) from Diyala Province in eastern Iraq. Specimens were gathered from different districts and habitats between July 2025 and June 2026. The species Arctosa tbilisiensis Mcheidze, 1946, Lycosa piochardi Simon, 1876, and Wadicosa fidelis (O. Pickard-Cambridge, 1872) are recorded for the first time in Diyala, extending their known ranges within Iraq. The paper describes key diagnostic morphological features and includes information about the examined specimens and their local distributions. These findings improve knowledge of the distribution of Iraqi Lycosidae and reveal that Diyala Province, despite its habitat variety, remains insufficiently studied. The records serve as a valuable baseline for future taxonomic, faunistic, and ecological research on spiders i...

Could venom-derived therapeutics resolve treatment resistance in refractory EAC?

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Could venom-derived therapeutics resolve treatment resistance in refractory EAC?

Abstract

The incidence of esophageal adenocarcinoma is rising in Western countries. Despite advances in chemotherapy and immunotherapy, the prognosis remains poor, with an overall 5-year survival rate below 15%. A major challenge is the cancer’s poor and often unpredictable response to current treatments. Animal venoms represent a promising yet underexplored source of therapeutic agents, offering millions of structurally diverse and highly potent bioactive peptides that can modulate a wide array of molecular targets. However, only a small fraction of these peptides has been pharmacologically characterized. This review presents the therapeutic potential of venom-derived peptides in cancer treatment, summarizes the role of ion channels in esophageal adenocarcinoma (EAC), and discusses peptides targeting ion channels that may offer new opportunities for future EAC treatment.

Freuville L, Matthys C, Gilliaux Q ...Could venom-derived therapeutics resolve treatment resistance in refractory EAC? Trends in Molecular Medicine, 2026; 0, 
https://www.cell.com/trends/molecular-medicine/fulltext/S1471-4914(26)00064-X