Clinical characteristics and long-term disabilities in children following Bothrops atrox envenomation in Manaus, western Brazilian Amazon

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  Image Credit: By Darío De la Fuente - https://www.inaturalist.org/photos/113840233, CC BY 4.0, https://commons.wikimedia.org/w/index.php?curid=129474300 Clinical characteristics and long-term disabilities in children following Bothrops atrox envenomation in Manaus, western Brazilian Amazon Abstract Background:   In the Brazilian Amazon, most snakebites are caused by Bothrops atrox . Although pediatric cases are less frequent, children are more vulnerable to severe complications and long-term disabilities. This study aims to describe the clinical profile of B. atrox envenomation in children treated at a tertiary hospital in Manaus, in Western Brazilian Amazon, and to characterize the resulting long-term musculoskeletal impairments in a subgroup of these patients. Methods:   We retrospectively analyzed sociodemographic and clinical data from patients up to 12 years and 11 months of age treated between January 2010 and December 2023. A total of 258 children who were ...

ERGA-BGE reference genome of Leviellus thorelli, a common orb-weaving spider representing the Zygiellidae family

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ERGA-BGE reference genome of Leviellus thorelli, a common orb-weaving spider representing the Zygiellidae family

Abstract

The Leviellus thorelli reference genome provides the first high-quality genomic resource for Zygiellidae, a family of orb-weaving spiders with a dynamic systematic history and distinct for constructing webs with a characteristic spiral-free sector. As part of the European Reference Genome Atlas (ERGA), we generated a chromosome-level assembly for L. thorelli that is organized into 13 contiguous chromosomal pseudomolecules. This chromosome-level assembly encompasses 2.20 Gb and is composed of 939 contigs and 130 scaffolds, with contig and scaffold N50 values of 5.4 Mb and 167.1 Mb, respectively. This genome represents a valuable addition to the growing collection of spider genomes. With Zygiellidae now included among the available genomes of true orb-weavers, this is a key resource for comparative studies into the genomic basis of orb web and silk evolution.

Gregorič M, Bužan E, Böhne A et al. ERGA-BGE reference genome of Leviellus thorelli, a common orb-weaving spider representing the Zygiellidae family [version 1; peer review: 2 approved]. Open Res Europe 2025, 5:365 (https://doi.org/10.12688/openreseurope.21671.1)