A new species of the mygalomorph spider genus Euagrus Ausserer (Araneae: Euagridae) from central Mexico and new records of E. gus Coyle from Tlaxcala

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  A new species of the mygalomorph spider genus Euagrus Ausserer (Araneae: Euagridae) from central Mexico and new records of E. gus Coyle from Tlaxcala Abstract  A new species of the spider genus Euagrus Ausserer, 1875 from temperate pine-oak forests in the states of Tlaxcala and Hidalgo, Mexico is described: E. pulque sp. nov. The description of the new species is based on male and female adult specimens. Additionally, Euagrus gus Coyle, 1988 is recorded for the very first time in the state of Tlaxcala. These species have sympatric distributions in La Malinche National Park, Tlaxcala. With this description, the diversity of the genus increases to 23 species, with Mexico harboring the highest diversity with 17 described species.  Valdez-Mondragón, A., Salinas-Velasco, H. V. & Bueno-Villegas, J. (2026). A new species of the mygalomorph spider genus Euagrus Ausserer (Araneae: Euagridae) from central Mexico and new records of E. gus Coyle from Tlaxcala. Zootaxa 5810 (...

Integration of proteomic and transcriptomic data of the venom and venom gland from Tityus jaimei

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Integration of proteomic and transcriptomic data of the venom and venom gland from Tityus jaimei

Abstract

This work presents a comprehensive transcriptomic and proteomic analysis of the venom gland and venom of Tityus jaimei, a recently described scorpion species of medical relevance in Panama and Costa Rica. High-throughput RNA sequencing (RNA-seq) and tandem mass spectrometry (MS/MS) enabled the identification of a diverse repertoire of venom proteins. Notably, this is the first report of proteins belonging to the nucleotide pyrophosphatase/phosphodiesterase and knottins families in the venom proteome of a scorpion from the genus Tityus. In addition, several known venom protein families were identified, including hyaluronidases, voltage-gated sodium and potassium channel toxins, lipolysis-activating peptides (LVPs), cysteine-rich secretory proteins (CRISPs), metalloproteinases, peptidylglycine alpha-hydroxylating monooxygenases (PHMs), serine proteases, alpha-amylases, single insulin-like growth factor-binding domain proteins, non-disulfide-bridged peptides (NDBPs), chitinases, cyclotide trypsin inhibitors, and calcin-like peptides. The identification of 16 distinct families in the venom of Tityus jaimei offers novel insights into its composition and the diversity of Tityus venoms in Central America. Finally, the use of IA to protein domain search for protein annotation.
Escobar, A., Salazar, M. H., Hernández-Ortiz, M., Clement, H., Encarnación, S., Cleghorn, J., Acosta, H., & Corzo, G. (2025). Integration of proteomic and transcriptomic data of the venom and venom gland from Tityus jaimei. Journal of Proteomics, 105543. https://doi.org/10.1016/j.jprot.2025.105543