Antitumor activity of scorpion venom-derived peptides: A meta-analysis of preclinical studies

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  Antitumor activity of scorpion venom-derived peptides: A meta-analysis of preclinical studies Abstract Despite advances in cancer therapeutics, there are still challenges in improving drug toxicity and selectivity. Peptides from various venous species have recently garnered attention for their biopharmaceutical potential, particularly in cancer. The present study aimed to conduct a meta-analysis of the antitumor activity of scorpion venom-derived peptides (SVDPs) previously reported in preclinical models. The bibliographic research included original and review articles written in English published from 2015 to 2026. Studies within the scope were retrieved from the EBSCO Discovery Service, PubMed, and WIPO databases. A total of 27 articles that met the inclusion and exclusion criteria were included in this research, and the collected data were synthesized through a meta-analysis. In the included in vitro and in vivo studies, the effect of SVDPs on breast/mammary gland, cervical,...

Spider wasps (Hymenoptera: Pompilidae) from Xiede (Eocene, central Tibetan Plateau): systematics and paleoecological implications

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Spider wasps (Hymenoptera: Pompilidae) from Xiede (Eocene, central Tibetan Plateau): systematics and paleoecological implications

Spider wasps (Pompilidae), best known for capturing and paralysing a spider to serve as food resource for the larva, commonly placed together in an underground nest, is represented by about 5000 extant species. The fossil record of this diverse family spans from the Eocene to the Miocene, with 26 occurrences to date, but only four of them are well-ascertained members of the Pompilinae, one of the most diverse Pompilidae subfamilies. Herein, we report two new records of fossil Pompilinae, namely Gubuzhu orientalis n. gen., n. sp. and Paleoferreolina xiedensis n. gen., n. sp., from the Xiede locality (Niubao Formation, Nima Basin, central Tibetan Plateau, China). The former species can be confidently assigned to the tribe Pompilini, while the latter shares morphological similarities with members of Aporini, as well as members of other tribes within Pompilidae. The two new species represent the earliest occurrences of Pompilinae, and the first ones at Asian deposits, suggesting that the subfamily was already widespread in the Northern Hemisphere during the late Eocene. More­over, Gubuzhu orientalis n. gen., n. sp. lacked a tarsal comb, indicating that it may have had a limited excavation activity in its nesting behaviour.

XU X.-T., WAICHERT C., DENG W.-Y., SU T. & BÉTHOUX O. 2025. — Spider wasps (Hymenoptera: Pompilidae) from Xiede (Eocene, central Tibetan Plateau): systematics and paleoecological implications. Geodiversitas 47 (6): 313-325. https://doi.org/10.5252/geodiversitas2025v47a6. http://geodiversitas.com/47/6