Molecular Recognition and Immunopharmacological Implications of Serratiopeptidase Targeting Snake Venom Bradykinin-Potentiating Peptides

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  Molecular Recognition and Immunopharmacological Implications of Serratiopeptidase Targeting Snake Venom Bradykinin-Potentiating Peptides Abstract Purpose Bradykinin-potentiating peptides (BPPs), found in snake venom, are known to modulate cardiovascular functions, but their susceptibility to enzymatic degradation remains poorly understood. Methods Models were generated using AlphaFold-Colab for five small BPPs (< 9 amino acids) that did not have experimentally solved structures, and those BPPs which had reliable predictions of structure (pLDDT > 80) were used for docking studies. Protein-peptide docking experiments were done using HADDOCK for studying the interaction between wild-type (WT) and mutant serratiopeptidase with BPPs. After selecting the best complex, simulation of the complex was done using molecular dynamics (MD) simulations for 100 ns and binding energy determination using MM/PBSA analysis. For checking the mechanical stability of the protein-peptide complexes...

What’s in the box? The establishment of Cheiracanthium furculatum Karsch, 1879 (Araneae, Cheiracanthiidae) in Europe

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What’s in the box? The establishment of Cheiracanthium furculatum Karsch, 1879 (Araneae, Cheiracanthiidae) in Europe

Abstract
Three specimens of Cheiracanthium furculatum Karsch, 1879 were found in lemon crops in the Campo de Cartagena subdivision of Murcia, Spain. These constitute the first records of the species in Spain. This species has been found before in other European countries where it has been linked to the importation of fruits and vegetables coming from various countries in Africa. However, these are the first records that are not strictly linked to imports, raising the question of whether the species may have become naturalised in the region.

Guibert Cañizares I, Fernández Martín D, Fernández Velasco L, Gallego Cambronero D (2026) What’s in the box? The establishment of Cheiracanthium furculatum Karsch, 1879 (Araneae, Cheiracanthiidae) in Europe. Check List 22(5): 835-839. https://doi.org/10.15560/22.5.835